Clinical study of Yinqi Guiyuan Acupuncture Combined with Repetitive Transcranial Magnetic Stimulation on the Treatment of Post-Stroke Fatigue:A Prospective Randomized Controlled Trial
10.13241/j.cnki.pmb.2025.20.003
- VernacularTitle:引气归元针法联合重复经颅磁刺激治疗脑卒中后疲劳的临床研究:一项前瞻性随机对照试验
- Author:
Min WANG
1
;
Fang-yuan CHENG
1
;
Yu-jing GUO
1
Author Information
1. 山西省中西医结合医院重症医学科 山西太原 030013
- Publication Type:Journal Article
- Keywords:
Yinqi Guiyuan acupuncture;
Repetitive transcranial magnetic stimulation;
Post-stroke fatigue;
Clinical efficacy;
Inflammatory factors;
Quality of life
- From:
Progress in Modern Biomedicine
2025;25(20):3220-3227
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy of Yinqi Guiyuan acupuncture combined with repetitive transcranial magnetic stimulation in the treatment of post-stroke fatigue(PSF).Methods:A prospective study was conducted,91 patients with PSF admitted to our hospital from May 2023 to October 2024 were included as the research subjects,and they were divided into control group(received conventional treatment combined with repetitive transcranial magnetic stimulation,n=45)and study group(received Yinqi Guiyuan acupuncture on the basis of the control group,n=46)according to random number table method.The clinical efficacy,inflammatory factors[C-reactive protein(CRP),interleukin-1[3(IL-1β),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)]and related scale score[pittsburgh sleep quality index(PSQI),Fugl-Meyer motor function assessment(FMA),fatigue severity scale(FSS),stroke specific quality of life scale(SS-QOL)]were compared between the two groups.Result:The total clinical effective rate of the study group were higher than that of the control group(P＜0.05).The levels of serum CRP,IL-1β,IL-6 and TNF-α after treatment in the study group were lower than those in the control group(P＜0.05).The PSQI and FSS score after treatment in the study group were lower than those in the control group,and the FMA and SS-QOL score were higher than those of the control group(P＜0.05).Conclusion:The synergistic intervention of Yinqi Guiyuan acupuncture and repetitive transcranial magnetic stimulation has multiple therapeutic benefits for PSF patients,which can not only significantly relieve clinical symptoms(including sleep disorders,fatigue levels and motor function disorders),but also improve the overall quality of life,and its mechanism of action may be related to the regulation of inflammatory factor expression.
