Application Effect of Concentrated Growth Factor Combined with Dual Antibacterial Drug Paste in Young Permanent Teeth Children with Pulp Necrosis
10.13241/j.cnki.pmb.2025.19.020
- VernacularTitle:浓缩生长因子联合二联抗菌药物糊剂在年轻恒牙牙髓坏死患儿中的应用效果
- Author:
Yue LI
1
;
Rong MENG
1
;
Li PENG
1
Author Information
1. 新疆生产建设兵团第二师库尔勒医院口腔科 新疆库尔勒 841000
- Publication Type:Journal Article
- Keywords:
Concentrated growth factor;
Dual antibacterial drug paste;
Young permanent teeth;
Pulp necrosis;
Children
- From:
Progress in Modern Biomedicine
2025;25(19):3186-3193
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the application effect of concentrated growth factor combined with dual antibacterial drug paste in young permanent teeth children with pulp necrosis.Methods:This study was a prospective study,79 young permanent teeth children with pulp necrosis who were admitted to our hospital from May 2022 to May 2023 were divided into control group(treated with conventional pulp revascularization combined with dual antibacterial drug paste,n=39 cases)and study group(treated with concentrated growth factor pulp revascularization combined with dual antibacterial drug paste,n=40 cases)according to the random number table method.Follow up for 12 months,the clinical efficacy,pain visual analogue scale(VAS),cementoid tissue deposition rate,root canal wall thickness,root length,bite force,chewing efficiency and satisfaction of the children's families were compared.Result:The total clinical effective rate in the study group was higher than that in the control group(P＜0.05).After 6 months and 12 months of treatment,the pain VAS scores decreased and cementoid tissue deposition rate increased between two groups,and the pain VAS scores in study group were lower than those in control group,the cementoid tissue deposition rate was higher than that in the control group(P＜0.05).After 6 months and 12 months of treatment,the root canal wall thickness and root length increased between two groups,and the root canal wall thickness and root length in the study group were higher than those in the control group(P＜0.05).After 6 months and 12 months of treatment,the bite force and chewing efficiency increased between two groups,and the inbite force and chewing efficiency in the study group were higher than those in control group(P＜0.05).The total satisfaction rate in study group was higher than that in control group(P＜0.05).Conclusion:Concentrated growth factor combined with dual antibacterial drug paste in young permanent teeth children with pulp necrosis can increase the total clinical efficacy,significantly increase cementoid tissue deposition rate and chewing ability,promote the regeneration of dental tissue,relieve pain,and the satisfaction of the children's families is relatively high.
