Research progress on the effects of anti-retroviral agents on glucose and lipid metabolism and body weight in patients with human immunodeficiency virus infection
10.3760/cma.j.cn114015-20240402-00219
- VernacularTitle:抗逆转录病毒药物对人类免疫缺陷病毒感染者糖脂代谢及体重影响的研究进展
- Author:
Ran XIAO
1
;
Xiaoli DU
;
Taisheng LI
Author Information
1. 中国医学科学院北京协和医学院北京协和医院药剂科，北京 100730
- Publication Type:Journal Article
- Keywords:
Anti-retroviral agents;
Anti-HIV Agents;
Glucose metabolism disorders;
Lipid metabolism disorders;
Body weight;
Human immunodeficiency virus
- From:
Adverse Drug Reactions Journal
2025;27(1):36-43
- CountryChina
- Language:Chinese
-
Abstract:
Antiretroviral therapy (ART) significantly improves the survival rate and quality of life of patients with human immunodeficiency virus (HIV) infection. However, with the extension of patients′ survival time, drug-induced new health problems such as blood glucose increase, dyslipidemia, and weight gain are becoming prominent. Different antiretroviral agents have different effects on blood glucose, blood lipid and adipose tissue. This paper reviews the research progress on effects of nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors, protease inhibitors, integrase inhibitors on blood glucose, lipid metabolism and body weight in HIV-infected people in recent years, and puts forward corresponding control suggestions.
