Clinical efficacy of PVP/PKP surgery on disc degeneration in patients with osteoporotic vertebral compression fractures
10.3760/cma.j.cn115807-20241105-00343
- VernacularTitle:经皮椎体成形术/后凸成形术对骨质疏松性椎体压缩骨折患者椎间盘退变的临床疗效
- Author:
Wenli LUO
1
;
Lyufang YING
;
Zongshan JIN
;
Sixiao ZHANG
Author Information
1. 宁波市杭州湾医院骨科，宁波 315300
- Publication Type:Journal Article
- Keywords:
Osteoporotic vertebral compression fractures;
PVP/PKP surgery;
Disc degeneration;
Vertebral re-fracture
- From:
Chinese Journal of Endocrine Surgery
2024;18(6):818-823
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine radiological and clinical data to investigate the influence of PVP/PKP surgery on disc degeneration and treatment outcomes in patients with osteoporotic vertebral compression fractures. Additionally, by analyzing clinical and radiological data, we aim to identify the risk factors for postoperative re-fracture in patients with osteoporotic vertebral compression fractures.Methods:This retrospective study collected clinical data from 100 patients who underwent PVP/PKP surgery and conservative treatment for osteoporotic vertebral compression fractures (OVCF) at our hospital from Jan. 2021 to Jan. 2023. Clinical characteristics of the included patients were collected, including demographic data, surgical duration, intraoperative blood loss, and volume of bone cement injected. Furthermore, the visual analog scale (VAS) scores, oswestry disability index (ODI) scores, radiographic measurements, anterior vertebral height, bone mineral density (BMD) T-scores, Cobb angle were collected for all patients during the one-year follow-up period, and to diagnose whether the patient developed a new vertebral fracture postoperatively.Results:Starting from the first month after surgery, the VAS scores and ODI scores of the PVP/PKP group were significantly lower than those of the conventional group ( P<0.05). Additionally, there were no significant differences in BMD T-scores, anterior vertebral height, or Cobb angle at all time points between the two groups of patients. Compared to OVCF patients in the non-re-fracture group, patients in the re-fracture group had significantly older age, significantly lower preoperative BMD T-scores, and significantly higher preoperative Cobb angles. Logistic regression analysis showed that preoperative BMD T-scores and preoperative Cobb angle were risk factors for vertebral re-fracture in OVCF patients within 1 year after surgery. Conclusions:This retrospective study demonstrates that PVP/PKP treatment effectively alleviates clinical symptoms in OVCF patients without increasing the risk of re-fracture. These findings provide new clinical evidence for the treatment of OVCF patients.
