Hot topics and research advances in perioperative immunotherapy for non-small cell lung cancer
10.3969/j.issn.1005-6483.20250814
- VernacularTitle:非小细胞肺癌围手术期免疫治疗热点问题及研究进展
- Author:
Xuehui LIU
1
;
Guochao ZHANG
;
Yufei HUANG
;
Fengwei TAN
Author Information
1. 100021 北京,中国医学科学院肿瘤医院胸外科;天津大学医学部
- Publication Type:Journal Article
- Keywords:
non-small cell lung cancer;
perioperative;
immunotherapy
- From:
Journal of Clinical Surgery
2025;33(9):938-942
- CountryChina
- Language:Chinese
-
Abstract:
Non-small cell lung cancer(NSCLC)continues to exhibit a high incidence and mortality worldwide,posing a serious threat to human health.In recent years,the rapid advancement of immunotherapy has profoundly reshaped the therapeutic paradigm for NSCLC,particularly by improving long-term outcomes in the perioperative period.However,with its increasingly widespread clinical use during this period,several critical issues have emerged,including the precise identification of patients most likely to benefit,optimization of therapeutic strategies,evaluation of pathological value,formulation of adjuvant therapy strategies for patients with complete pathological response after surgery,and the management of immune-related adverse events.This review will systematically discuss these key challenges and aims to provide insights that may facilitate the standardized application of perioperative immunotherapy in NSCLC.
