Drug-induced neurological disorders: from current diagnosis and treatment to future research
10.3760/cma.j.cn114015-20241016-00095
- VernacularTitle:药源性神经系统疾病：从当前诊疗到未来研究
- Author:
Xuefan YAO
1
;
Yuan WANG
1
;
Haiqing SONG
1
Author Information
1. 首都医科大学宣武医院神经内科，北京 100053
- Publication Type:Journal Article
- Keywords:
Nervous system diseases;
Abnormalities, drug-induced;
Diagnosis;
Therapy;
Adverse drug reactions
- From:
Adverse Drug Reactions Journal
2025;27(2):79-83
- CountryChina
- Language:Chinese
-
Abstract:
Drug-induced neurological disorders (DINDs) refer to the central or peripheral nervous system disease caused by drugs. DINDs account for a large proportion of adverse drug reactions/events in China, and its onset is complex to some extent. Common DINDs include epilepsy, movement disorders, stroke, peripheral neuropathy, spinal cord injury, cognitive impairment and so on. Usually, DINDs have characters of gradual development and late-onset reactions, and it is difficult to associate their clinical manifestations with drugs, leading to misdiagnosis and poor prognosis in clinic. To reduce the neurotoxicity of drugs, multidisciplinary cooperation should be strengthened, and individualized treatment plans for high-risk people and closer monitoring should be implemented for timely identification and diagnose. At the same time, relevant researches on DINDs should be strengthened in the clinic to cope with the complexity and long-term prognosis challenges of the diseases.
