Radiofrequency Ablation for T1N0M0 Papillary Thyroid Carcinoma with Rich Blood Supply Versus Poor Blood Supply
10.3969/j.issn.1005-5185.2025.01.005
- VernacularTitle:富血供与乏血供T1N0M0甲状腺乳头状癌射频消融疗效比较
- Author:
Jiayi HE
1
;
Mingbo ZHANG
;
Haoyu JING
;
Xinyang LI
;
Lin YAN
;
Jing XIAO
;
Zhen YANG
;
Yukun LUO
Author Information
1. 解放军医学院,北京 100853;解放军总医院第一医学中心超声诊断科,北京 100853
- Publication Type:Journal Article
- Keywords:
Thyroid cancer,papillary;
Radiofrequency ablation;
Treatment outcome;
Contrast-enhanced ultrasound
- From:
Chinese Journal of Medical Imaging
2025;33(1):26-32
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the long-term efficacy of radiofrequency ablation(RFA)for T1N0M0 papillary thyroid carcinoma(PTC)with rich blood supply and poor blood supply.Materials and Methods Clinical data,ultrasound and contrast-enhanced ultrasound(CEUS)images,RFA parameters,and postoperative follow-up indicators of 375 T1N0M0 PTC patients who received RFA from June 2014 to December 2018 were retrospectively collected.The propensity score matching method was used to match the baseline data of the two groups in a 1:1 ratio,finally a total of 212 patients were included in the study.The RFA parameters,volume,tumor disappearance,and local tumor progression(LTP)were compared between the groups.Besides,the correlation between rich blood supply and LTP was analyzed using multivariate COX regression.Results According to the peak intensity displayed by preoperative CEUS,all lesions were divided into a group with rich blood supply(n=129)and another with poor blood supply(n=246).After a mean follow-up time of(84.48±14.44)months,the tumor disappearance in the rich blood supply group was 87.74%,while in the poor blood supply group it was 88.68%,and there was no statistically significant difference(Z=0.05,P=0.831).There were 10 cases of LTP in the rich blood supply group(6 cases of residual cancer and 4 cases of new cancer),and 6 cases of LTP in the poor blood supply group(2 cases of residual cancer and 4 cases of new cancer).The LTP rates of the two groups were 9.43%and 5.67%,with no statistically significant difference(x2=1.08,P=0.298).The Kaplan-Meier survival curve showed no statistically significant difference in progression free survival between both groups(P=0.265).The adjusted multivariate COX proportional risk model analysis showed that rich blood supply was no association with LTP(HR=1.54,P=0.409).Conclusion RFA for T1N0M0 PTC with rich blood supply can achieve effective ablation,and its long-term efficacy is similar to that of poor blood supply.RFA can serve as an effective alternative treatment for T1N0M0 PTC patients with different blood supply.
