Application of glucagon-like peptide-2 analogues in children with short bowel syndrome: a report of 2 cases

VernacularTitle:替度格鲁肽在儿童短肠综合征应用2例
Author: Lina LU ¹ ; Haixia FENG ; Liufang HUANG ; Weihui YAN ; Ying WANG ; Wei CAI
Author Information

1. 上海交通大学医学院附属新华医院儿消化营养科，上海　200092
Publication Type:Journal Article
Keywords: Short bowel syndrome; Teduglutide; Glucagon-like peptide-2 analogues; Parenteral nutrition
From: Chinese Journal of Clinical Nutrition 2024;32(6):373-377
CountryChina
Language:Chinese
Abstract: Children with short bowel syndrome (SBS) mainly rely on long-term parenteral nutrition to obtain adequate nutrients until the length and function of the small intestine are improved. In recent years, the clinical application of human glucagon-like peptide 2 analogue Teduglutide has made it more likely for SBS patients to discontinue parenteral nutrition as early as possible and achieve intestinal functional autonomy. This paper reports two cases of SBS children who were treated with Teduglutide combined with parenteral and enteral nutrition for intestinal rehabilitation, and finally got rid of parenteral nutrition. According to the author, there have been no reports of pediatric children using Teduglutide in China.