Visualization Analysis of the Current Research Status of Chinese Materia Medica Treatment for Parkinson's Disease
10.11842/wst.20250225004
- VernacularTitle:中药治疗帕金森病研究现状的可视化分析
- Author:
Weizhou CHEN
1
;
Ping YIN
;
Xia LI
;
Die HU
;
Zhenyu GUO
;
Cong GAI
;
Huimin ZHU
Author Information
1. 北京中医药大学中药学院 北京 100029
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Chinese materia medica;
Knowledge graph;
Bibliometrics;
CiteSpace;
Visual analysis
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2025;27(11):3276-3294
- CountryChina
- Language:Chinese
-
Abstract:
Objective To give references for future study,the current state of research and identify key areas of interest,and development trends in the field of Chinese Materia Medica interventions for PD were examined.Methods Literature on Chinese Materia Medica treatment of PD published between 2004 and 2024 was retrieved from the China National Knowledge Infrastructure(CNKI)and Web of Science(WOS)databases.After screening,689 articles were included(412 in Chinese,277 in English).CiteSpace software was used for bibliometric and knowledge graph analysis,generating author collaboration networks,institutional collaboration networks,keyword clustering,timeline maps,and keyword burst analysis.Results Over the past two decades,the number of publications has continued to grow globally.Chinese-language studies focused primarily on clinical research,with core authors such as Yi Liu,Jiancheng He,and Jianfen Liang,and institutions like Guangxi University of Chinese Medicine making significant contributions.English-language literature emphasized mechanistic studies,with Kyung Hee University and Beijing University of Chinese Medicine as leading research teams.High-frequency keywords included"Parkinson's disease"(346 occurrences),"traditional Chinese medicine(TCM)"(60 occurrences),and"oxidative stress"(11 occurrences).Keyword clustering revealed research hotspots in TCM formulas(e.g.,Zhichan decoction),mechanisms(e.g.,oxidative stress),and integrated TCM-Western medicine therapies(e.g.,Madopar).Burst analysis indicated emerging frontiers in the gut-brain axis,iron metabolism,molecular docking,gut microbiota,and signaling pathways.Conclusions Although there is a lot of potential for treating PD in TCM,there are also a lot of challenges.In order to realize the transformation of TCM from a supportive to a mainstream treatment for PD,and to bring better efficacy to patients in the future,it is necessary to strengthen evidence-based research,deepen the research of mechanisms,promote the construction of standards,explore the integration of Chinese and Western medicine,and improve the evaluation system.
