Practical experience in genetic counseling for sperm donors in human sperm bank
10.3760/cma.j.cn101441-20250319-00128
- VernacularTitle:人类精子库供精者遗传咨询的实践经验
- Author:
Liu LIU
1
;
Yong ZHU
;
Guoqing LIANG
;
Hong ZHU
;
Feng JIANG
Author Information
1. 复旦大学附属妇产科医院人类精子库，上海 200011
- Publication Type:Journal Article
- Keywords:
Sperm bank;
Genetic counseling;
Genetic screening;
Genetic matching
- From:
Chinese Journal of Reproduction and Contraception
2025;45(8):861-864
- CountryChina
- Language:Chinese
-
Abstract:
Based on the practical experience of the Human Sperm Bank, Obstetrics and Gynecology Hospital, Fudan University, this paper explores the necessity, core content, process, and common challenges of genetic counseling for sperm donors, while proposing optimization strategies. Genetic counseling for sperm donors employs methods such as family history investigation, karyotype analysis, high-throughput gene sequencing, and genetic matching to effectively identify and mitigate hereditary risks in donor-conceived offspring, thereby enhancing the scientific rigor and operability of sperm bank quality control systems. Addressing challenges such as donor acceptance, technological limitations, the complexity of genetic matching, ethical issues and privacy protection, and long-term health monitoring, this paper suggests strategies including optimizing genetic screening protocols, establishing intelligent genetic matching systems, strengthening privacy protection mechanisms, and improving long-term health management. The aim of this paper is to provide a scientific and practical reference for professionals to optimize genetic counseling management in sperm banks, ensuring sperm donor quality and the safety of assisted reproduction.
