Study on Gait Characteristics of Patients with Cognitive Impairment in Different Frailty States
10.11969/j.issn.1673-548X.2025.10.015
- VernacularTitle:不同衰弱状态下认知障碍患者的步态特征研究
- Author:
Shanshan CHENG
1
;
Tongfu QIAO
;
Wanfei SUN
Author Information
1. 215006 苏州大学附属第一医院老年医学科
- Publication Type:Journal Article
- Keywords:
Cognitive impairment;
Gait;
Frailty;
Pre-frailty
- From:
Journal of Medical Research
2025;54(10):84-88
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the gait characteristics of patients with cognitive impairment in three different frailty states,and explore sensitive gait parameters that can effectively distinguish between their different frailty states,providing a reference for the assess-ment and intervention of frailty in patients with cognitive impairment.Methods A retrospective study was conducted.116 patients with cognitive impairment who visited the Memory Impairment Clinic of the First Affiliated Hospital of Soochow University from October 2022 to November 2023 were included.Gait parameters were collected using the Mobility LabTM APDM Opal wearable system from the United States,and general clinical data and gait assessment results were analyzed.Results Among the 116 patients with cognitive impairment,24 patients were in the frailty phase,67 patients were in the pre-frailty phase,and 25 patients were in the non-frailty phase.Multivari-ate logistic regression analysis showed that walk velocity,stride length,double stance phase,and swing phase were significantly correlated with the frailty states of patients with cognitive impairment.Receiver operating characteristic(ROC)curve analysis showed that walk ve-locity,stride length,double stance phase,and swing had high predictive value for the frailty states of patients with cognitive impairment.Conclusion Compared with patients with cognitive impairment with non-frailty,patients with cognitive impairment and frailty had more significant gait disorders.Among them,the pre-frailty group mainly presented with reduced walk velocity and shortened stride length,while the frailty group,in addition to the reduced walk velocity and shortened stride length,also showed prolonged double stance phase and shortened swing phase.Walk velocity,stride length,double stance phase and swing phase are sensitive indicators for identifying dif-ferent frailty states in patients with cognitive impairment.
