Application of ultrasound-guided injection of carbon nanoparticle in cervical lymph node dissection for thyroid cancer reoperation
10.3760/cma.j.cn115807-20240709-00236
- VernacularTitle:超声引导下注射纳米炭在甲状腺癌再次手术颈淋巴结清扫中的应用
- Author:
Yue ZHOU
1
;
Gang WANG
;
Fang YU
;
Hao XU
;
Zhenyu CHENG
;
Ziyi FAN
;
Xianjiao CAO
;
Zhonghui LI
;
Qingqing HE
Author Information
1. 山东中医药大学第一临床医学院，济南 250000
- Publication Type:Journal Article
- Keywords:
Thyroid;
Ultrasound guidance;
Carbon nanoparticle;
Papillary thyroid carcinoma;
Reoperation;
Lymph node dissection
- From:
Chinese Journal of Endocrine Surgery
2025;19(1):30-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy of preoperative ultrasound-guided injection of carbon nanoparticle suspension in cervical lymph node dissection for thyroid cancer reoperation.Methods:Ninety-four patients undergoing reoperation for thyroid cancer admitted by the same physician team of the Department of Thyroid and Breast Surgery of the Ninety-sixty Hospital of the People’s Liberation Army (PLA) from Jan. 2019 to Sep. 2024 were retrospectively analyzed. According to the different scope of the initial surgery, they were divided into the re-specification clearance group, the regional lymph node clearance group, and the metastatic lymph node dissection group, and the groups were subdivided into the carbon nanoparticle group and the control group according to whether they were injected with carbon nanoparticle before the surgery or not. The t-test, χ2-test, and non-parametric test were used to compare the age, gender, surgical method, duration of surgery, total number of lymph nodes detected, and positive lymph node detection rate between the nano-charcoal group and the control group in the three groups. Results:There was no statistically significant difference between the three groups in terms of age, gender, surgical methods, or the total number of lymph nodes detected (all P>0.05) , and the difference between the surgical time of the carbon nanoparticle group in the re-regulation clearance group and the control group was not statistically significant ( P>0.05) ; the surgical time of the carbon nanoparticle group was shorter than that of the control group in both the regional lymph node clearance and the metastatic lymph node dissection groups, and the difference was statistically significant (all P<0.05) ; the positive detection rate of lymph nodes in the carbon nanoparticle group was higher than that in the control group among the three groups, and the difference was statistically significant (all P<0.05) . Conclusion:In the operation of cervical lymph node dissection for papillary thyroid cancer, preoperative ultrasound-guided injection of carbon nanoparticle can accurately localize the lymph nodes, increase the positive detection rate of lymph nodes, reduce the difficulty of surgical operation, and shorten the operation time.
