Negative effects of radionuclides on male reproduction
10.3760/cma.j.cn101441-20250725-00314
- VernacularTitle:放射性核素对男性生殖的负效应
- Author:
Weijie ZHU
1
Author Information
1. 暨南大学生命科学技术学院生殖免疫研究所，广州 510632
- Publication Type:Journal Article
- Keywords:
Radionuclide;
Ionizing radiation;
Male reproduction;
Testis;
Sperm
- From:
Chinese Journal of Reproduction and Contraception
2025;45(11):1081-1086
- CountryChina
- Language:Chinese
-
Abstract:
The cells within the male reproductive system have a molecular material basis for binding and retaining radionuclides. Radionuclides can cause ionizing radiation damage and genotoxicity to the cells of the male reproductive system through mechanisms such as thermal effects and oxidative stress, leading to corresponding changes in cell structure and function, even cell death, and inducing nuclear genetic material abnormalities or even mutagenesis, resulting in a high risk of genetic or epigenetic defects in offspring. Strengthening the protection, monitoring, and investigation of radionuclides in male reproduction will help prevent damage to the male reproductive system caused by radionuclides, thereby ensuring physical health, including male reproductive health.
