Physiological functions of prokineticin 2 and its role in reproductive system diseases
10.3760/cma.j.cn101441-20250418-00193
- VernacularTitle:前动力蛋白2的生理功能及在生殖系统疾病中的作用
- Author:
Yaping LIU
1
;
Jun ZHAI
1
Author Information
1. 郑州大学第一附属医院生殖医学中心，郑州 450052
- Publication Type:Journal Article
- Keywords:
Prokineticin 2;
Prokineticin receptors;
Biological functions;
Reproductive system diseases
- From:
Chinese Journal of Reproduction and Contraception
2025;45(10):1072-1076
- CountryChina
- Language:Chinese
-
Abstract:
Prokineticin 2 (PK2) is a secretory protein containing multiple cysteines with various biological functions, participating in numerous physiological processes in the body. Abnormal expression of PK2 and its signaling pathways can lead to diseases in various systems of the body, including the nervous system, digestive system, immune system, reproductive system, and others. This article will focus on a comprehensive review of the physiological functions of PK2 and its role in reproductive system diseases, aiming to provide theoretical support for the prevention and treatment of infertility and pregnancy-related disorders.
