A case of recurrence early-stage endometrial cancer during pregnancy recieved fertility-preserving retreatment
10.3760/cma.j.cn101441-20241025-00384
- VernacularTitle:早期子宫内膜癌患者孕期复发再次保留生育功能治疗1例
- Author:
Jing ZHANG
1
;
Wenyan TIAN
1
;
Ye TIAN
1
;
Yan ZHANG
1
;
Xiaohong BAI
1
;
Xueru SONG
1
;
Yingmei WANG
1
Author Information
1. 天津医科大学总医院妇产科 天津市女性生殖健康与优生重点实验室，天津300052
- Publication Type:Journal Article
- Keywords:
Endometrial cancer;
Early stage;
Preimplantation genetic testing;
Fertility-preserving treatment
- From:
Chinese Journal of Reproduction and Contraception
2025;45(6):623-627
- CountryChina
- Language:Chinese
-
Abstract:
A retrospective analysis was conducted on a case of recurrence during pregnancy of early-stage endometrial cancer (EEC) after fertility-preserving treatment, and literature review was conducted. The patient underwent two cycles of controlled ovarian stimulation and three cycles of frozen-thawed embryo transfer after fertility-preserving treatment, early abortion after the third transfer and meanwhile the recurrence of endometrial cancer was found. Fertility-preserving retreatment was given after multidisciplinary discussion based on the patient's fertility intention, ultrasound, pelvic magnetic resonance imaging and other examinations. After complete remission, the remaining cryopreserved embryos of the patient were tested for euploidy by preimplantation genetic testing, and the euploid embryo was transferred and delivered at term successfully. Fertility-preserving treatment for patients with EEC need comprehensive management to reduce the recurrence rate. Recurrent patients can choose fertility-preserving retreatment under a comprehensive evaluation.
