Application and research progress of estrogen in endometrial repair
10.3760/cma.j.cn101441-20250211-00055
- VernacularTitle:雌激素在子宫内膜修复中的应用及研发进展
- Author:
Bibi WANG
1
;
Yiqi CHEN
;
Yilin GUO
;
Sheng LI
;
Min CHEN
;
Yi WANG
;
Yan CHE
;
Linglin FENG
Author Information
1. 东华大学化学与化工学院 东华大学先进低维材料中心，上海 201620
- Publication Type:Journal Article
- Keywords:
Estrogen;
Endometrial injury;
Medical preparations;
Application;
Research progress
- From:
Chinese Journal of Reproduction and Contraception
2025;45(9):896-901
- CountryChina
- Language:Chinese
-
Abstract:
Estrogen, through binding to its receptors in the female endometrium, promotes the proliferation, differentiation, and angiogenesis of endometrial stromal cells, thereby playing a critical role in endometrial injury repair, regeneration, and the prevention and treatment of intrauterine adhesions. Currently, various estrogen-based pharmaceutical formulations are applied in clinical practice, and the development of related products is progressively advancing. This review systematically outlines the etiology of endometrial injury and the mechanisms by which estrogen facilitates endometrial repair and regeneration. Furthermore, it highlights recent research progress and clinical applications of estrogen-based therapies in endometrial regeneration, aiming to provide a valuable reference for relevant scientific research and clinical practice.
