Research progress of mosaic embryo transfers
10.3760/cma.j.cn101441-20250418-00192
- VernacularTitle:嵌合型胚胎移植的研究进展
- Author:
Jialiu LIU
1
;
Yanwen XU
1
Author Information
1. 中山大学附属第一医院生殖医学中心 广东省妇产科疾病临床医学研究中心 广东省生殖医学重点实验室，广州 510080
- Publication Type:Journal Article
- Keywords:
Embryo transfer;
Mosaicism;
Preimplantation genetic testing
- From:
Chinese Journal of Reproduction and Contraception
2025;45(8):775-778
- CountryChina
- Language:Chinese
-
Abstract:
The clinical application of preimplantation genetic testing (PGT) has revealed a prevalent incidence of chromosomal mosaicism in human embryos. Although mosaic embryo transfer can yield healthy live births, the risk of pregnancy outcomes and offspring safety remains uncertain. This article comprehensively evaluates the clinical value of mosaic embryo transfer based on current evidence, focusing on the incidence of mosaicism, self-correction mechanisms, pregnancy outcomes, and offspring safety of mosaic embryo transfers. The findings offer evidence-based guidance for the clinical management of mosaic embryos.
