Comparison of the efficacy and safety between 1 470 nm laser en bloc resection of bladder tumor and transurethral resection of bladder tumor in treatment of non-muscle-invasive bladder cancer
- VernacularTitle:1 470 nm激光经尿道膀胱肿瘤整块切除术与经尿道膀胱肿瘤切除术治疗非肌层浸润性膀胱癌的安全性和有效性比较
- Author:
Yang WANG
1
;
Weiting PANG
;
Weifeng YANG
;
Haitian HE
;
Xinming ZHANG
;
Nan ZHANG
;
Kebing WANG
Author Information
- Publication Type:Journal Article
- Keywords: 1 470 nm laser; laser therapy; en bloc resection; transurethral resection of bladder tumor(TUR-BT); non-muscle-invasive bladder cancer(NMIBC)
- From: China Journal of Endoscopy 2025;31(1):80-85
- CountryChina
- Language:Chinese
- Abstract: Objective To compare the clinical efficacy and safety of 1 470 nm laser en bloc resection of bladder tumor(1 470 nm-EBRBT)and transurethral resection of bladder tumor(TUR-BT).Methods Clinical data of 85 non-muscle-invasive bladder cancer(NMIBC)patients from June 2018 to June 2021 were analyzed retrospectively.The patients were divided into 1 470 nm-EBRBT group(n=40)and TUR-BT group(n=45)according to different surgical methods,the postoperative chemotherapy regimen of bladder perfusion was the same in both groups.The surgical safety,clinical efficacy,pathological results and recurrence free survival rate of two groups were recorded.Results There were no statistically significant differences in operation time,incidence of bladder perforation,and incidence of postoperative delayed hemorrhage between the two groups(P＞0.05).Compared with the TUR-BT group,the 1 470 nm-EBRBT group had less blood loss,shorter bladder irrigation time,catheter indwelling time and postoperative hospital time,and no obturator nerve reflex,the differences were statistically significant(P＜0.05).The proportion of detrusor in the first resected pathological specimens in 1 470 nm-EBRBT group was higher than that in TUR-BT group(P＜0.05).There were no statistically significant differences in tumor recurrence rate of one year,tumor cumulative recurrence rate of two years and recurrence free survival time between the two groups(P＞0.05).Conclusion Compared with traditional TUR-BT,1 470 nm-EBRBT is a safe and effective method,which has the advantages of complete pathological specimens,fewer complications,faster recovery and so on.Therefore,it is worthy of clinical application.
