Effect of estimated pulse wave velocity changes on cardiovascular and cerebrovascular events
10.20039/j.cnki.1007-3949.2024.12.008
- VernacularTitle:估算的脉搏波传导速度的变化对心脑血管事件的影响
- Author:
Guodong WANG
1
;
Jinmei WANG
;
Chunpeng JI
;
Yan LIU
;
Na WANG
;
Zhe HUANG
Author Information
1. 开滦总医院员工健康保障中心
- Publication Type:Journal Article
- Keywords:
estimated pulse wave velocity;
cardiovascular and cerebrovascular events;
Cox regression model
- From:
Chinese Journal of Arteriosclerosis
2024;32(12):1067-1073
- CountryChina
- Language:Chinese
-
Abstract:
Aim To explore the effect of estimated pulse wave velocity(ePWV)changes on cardiovascular and cerebrovascular events.Methods A total of 61 714 employees who participated in the 2006-2007 physical examina-tion and 2010-2011 physical examination of Kailuan Group were selected as the research subjects.The subjects were di-vided into four groups according to the ePWV values at baseline and at the end of the observation period:sustained normal group,normal-high group,high-normal group and sustained high group,Cox regression model was used to analyze the effect of different changes of ePWV on cardiovascular and cerebrovascular events.Results A total of 3 715(6.02％)cases of cardiovascular and cerebrovascular events occurred after a mean follow-up of(8.52±1.59)years.The incidence density of cardiovascular events was 3.81,10.80,13.54 and 15.85 per 1 000 person-year respectively in the sustained nor-mal group,the normal-high group,the high-normal group and the sustained high group.After adjusting for confounders,the risk of cardiovascular and cerebrovascular events was significantly increased in the normal-high group,the high-normal group and the sustained high group compared with the sustained normal group,the HR(95％CI)were 2.68(2.44～2.95),3.14(2.67～3.69)and 4.03(3.71～4.38),respectively.Conclusion Maintaining normal ePWV can effectively reduce cardiovascular and cerebrovascular events.
