Exploring the Mechanism of Chinese Medicine in Treating Asthma Based on the Function of Bone Marrow Mesenchymal Stem Cells
- VernacularTitle:基于骨髓间充质干细胞功能阐释中医药治疗哮喘的作用机理
- Author:
Hongjuan HE
1
;
Xiaoyan JI
;
Xiaoyu WANG
;
Lihua CAO
;
Zhenzhen WANG
;
Mingsan MIAO
Author Information
- Publication Type:Journal Article
- Keywords: Asthma; Bone mesenchymal stem cell; Kidney essence; Chinese medicine; Mechanism
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(12):3204-3208
- CountryChina
- Language:Chinese
- Abstract: According to the theory of traditional Chinese medicine,the pathogenesis of asthma is the deficiency of kidney essence.Many drugs with kidney tonic function can regulate immune response and inhibit the occurrence of asthma.The kidney is considered to be congenital origin.The kidney is the place to store essence.It is believed that the kidney governs bone and generates marrow.The filling of kidney essence is related to the sufficiency of vital energy and blood in each viscera.When the kidney is full,the marrow is solid.Its fullness is related to the rise and fall of qi and blood in all organs.There are many similarities between the theory of kidney filling and the potential of bone marrow mesenchymal stem cells(BMSCs).The migration of BMSCs into the lung can inhibit the occurrence and development of asthma,and kidney tonic drugs can significantly regulate the proliferation,differentiation and migration of BMSCs.Therefore,the author believeed that kidney tonic drugs may affect the occurrence of asthma through regulating epithelial cells by stimulating the migration of BMSCs.This study will explore the role of BMSCs function in the treatment of asthma and analyze that the therapeutic effect of Chinese medicine on asthma is related to the function of BMSCs.
