Research progress of neutrophils in endometriosis

VernacularTitle:中性粒细胞在子宫内膜异位症中的研究进展
Author: Yunlei CAO ¹ ; Jing DU
Author Information

1. 复旦大学附属妇产科医院普妇科，上海　200011
Publication Type:Journal Article
Keywords: Endometriosis; Immunology; Cytokine; Neutrophils; Neutrophil extracellular traps
From: Chinese Journal of Reproduction and Contraception 2025;45(8):841-845
CountryChina
Language:Chinese
Abstract: Endometriosis (EMS) is one of the most common clinical gynecological diseases, which mainly causes dysmenorrhea, chronic pelvic pain and infertility. The incidence of EMS in women of childbearing age is as high as 10%, which brings great harm to women's physical and mental health. There are many theories about the pathogenesis of EMS. So far, no single hypothesis can fully explain its occurrence. Numerous studies have demonstrated chronic inflammatory reactions in the peritoneal cavity of patients with EMS, and multiple immune cells and cytokines are involved in this process. Therefore, the role of immune factors in the occurrence and development of EMS has become the focus of recent research. Neutrophils, as the main participants in the process of inflammatory response, have received wide attention in the study of endometriosis. This paper reviews the research progress on neutrophils in EMS.