Home Medication Adherence and Its Influencing Factors Among Elderly Patients with Chronic Diseases in China:A National Cross-sectional Survey
10.3870/j.issn.1004-0781.2025.12.011
- VernacularTitle:中国老年慢性病患者居家用药依从性现状及影响因素:基于全国横断面调查
- Author:
Wei ZHAO
1
;
Zhigang ZHAO
1
;
Mingfen WU
1
Author Information
1. 首都医科大学附属北京天坛医院药学部,北京 100070
- Publication Type:Journal Article
- Keywords:
Medication adherence;
Older adults;
Chronic disease;
Home medication;
Influencing factor
- From:
Herald of Medicine
2025;44(12):1948-1955
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess home medication adherence among elderly patients with chronic diseases in China,analyze influencing factors,and propose targeted intervention strategies.Methods A cross-sectional survey was conducted from October 2024 to March 2025,covering elderly patients(≥60 years)with chronic diseases across 31 provinces in China.Data were collected through face-to-face interviews by pharmacists,and binary logistic regression analysis was used to examine influencing factors and their interaction effects.Results A total of 6 692 valid questionnaires were collected(response rate:98.47%).The rate of optimal medication adherence was 36.86%(2 467 cases).Facilitators included:female sex(OR=0.869,P=0.040),higher education(junior high school:OR=0.690,P=0.001;senior high/vocational school:OR=0.782,P=0.014),regular disease monitoring(OR=1.443,P=0.033),awareness of medication indications(OR=0.662,P=0.025),ability to describe adverse drug reactions(OR=1.548,P﹤0.01),reviewing drug instructions before use(OR=1.384,P=0.015),and higher medication literacy(OR=0.980,P﹤0.01).Barriers included:larger household size(OR=1.058,P=0.001),employment status(OR=0.731,P=0.001),medical insurance coverage(OR=0.791,P=0.002),and drug-related problems(OR=1.899,P﹤0.01).Educational level plays a pivotal moderating role in the interaction effects.Conclusions Medication adherence among Chinese elderly chronic disease patients remains suboptimal and is influenced by multidimensional factors.Tailored,stratified interventions integrating medical,psychosocial,and pharmaceutical management strategies are warranted to achieve precision care.
