Configuration and service utilization analysis of preimplantation genetic diagnosis in China
10.3760/cma.j.cn101441-20240516-00175
- VernacularTitle:我国胚胎植入前遗传学诊断技术配置和服务利用分析
- Author:
Fu BAI
1
;
Yi MA
;
Lina GAO
;
Yixin ZHANG
;
Dongying WANG
;
Zhixin LI
Author Information
1. 国家卫生健康委妇幼健康中心，北京 100081
- Publication Type:Journal Article
- Keywords:
Preimplantation genetic diagnosis;
Technology configuration;
Service utilization
- From:
Chinese Journal of Reproduction and Contraception
2024;44(11):1180-1183
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the configuration characteristics, service utilization trend and outcome of preimplantation genetic diagnosis (PGD) in China.Methods:A longitudinal study and a cross-sectional survey in 2020 were used to analyze the number of PGD facilities and the trend of service utilization in China from 2004 to 2020. The characteristics of 2020 technology configuration were described from different geographical distribution, city positioning, and organization categories. The number of couples treated, the number of egg retrieval cycles and the number of diagnostic cycles were used to evaluate the scale of the service.Results:From 2004 to 2020, the number of PGD institutions increased from only 4 (10.8%) in 2004 to 78 (19.0%) in 2020. Although the number of PGD cycles increased with it, the overall proportion was not high, ranging from 0.3% to 4.1%. A total of 21 241 PGD cycles were reported in 2020, accounting for 4.1% of the total number of egg retrievals. The PGD technology configuration in 2020 was mainly characterized by provincial capitals [82.1% (64/78)], public hospitals [94.9% (74/78)], and comprehensive hospitals [59.0% (46/78)]. There were significant differences in the median of the number of PGD egg retrieval cycles in eastern, central and western institutions, which were 203.0, 177.5 and 79.0, respectively. In 2020, the PGD clinical pregnancy rate was 60.2% (10 326/17 158), the delivery rate was 51.1% (8 767/17 158), the multiple delivery rate was 1.9% (163/8 767), totally with 8 904 live births.Conclusion:After more than 20 years of rapid development of PGD technology in China, the geographical accessibility has been significantly improved. PGD services are small and uneven. Comprehensive hospitals in the capital cities of the eastern and central regions are the main features of the technical configuration, and prefecture-level institutions and institutions in the western regions have also become important providers of PGD technology.
