Value of Two-Dimensional Transverse Section of Thalamus in Evaluating the Developmental Status of Lateral Fissure of Fetus
10.3969/j.issn.1005-5185.2024.12.013
- VernacularTitle:二维超声丘脑横切面评估大脑外侧裂发育
- Author:
Zhongqiang ZHU
1
;
Xingyun WANG
;
Ling REN
Author Information
1. 赣南医科大学第一临床医学院,江西 赣州 341000
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Fetal development;
Sylvian fissure
- From:
Chinese Journal of Medical Imaging
2024;32(12):1262-1265,1276
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the value of two-dimension thalamic horizontal transverse section in the assessment of normal fetal lateral fissure development at 20-36+6 weeks. Materials and Methods It was a prospective cross-sectional study,normal single pregnant women who were examined in the First Affiliated Hospital of Gannan Medical University from March 1,2023 to March 1,2024 were selected for fetal brain imaging via two-dimensional ultrasound imaging technology. The morphology of lateral fissure of 272 normal fetuses at 20-36+6 weeks were observed with two-dimensional transverse section of thalamus. Lateral cleft width and depth were measured at a two-dimensional thalamic horizontal cross-section and a reference range of normal fetal lateral cleft width and depth was established at 20-36+6 weeks. The repeatability of lateral crack width and depth measurements within and between observers were all verified. Results A total of 272 normal fetuses of 20-36+6 weeks were enrolled in the study. A range of reference values for lateral cleft width and depth of normal fetus at 20-36+6 weeks of normal gestation was established. The lateral fetal fissure width and depth increased linearly with gestational age. The lateral fetal fissure width (mm)=-16.92+1.18 gestational age,and the lateral fetal fissure depth (mm)=-9.77+0.86 gestational age,with good intra-and inter-observer agreement (intra-class correlation coefficient,ICC>0.850). More than 95％ of the points in each Bland-Altman plot fall within the 95％ consistency limit. Conclusion Two-dimensional thalamic horizontal transverse section can be used to observe the morphological changes of lateral fella in middle and late pregnancy. It is a simple and feasible method for prenatal assessment of cerebral cortex development,and can be used to guide follow-up,referral,prenatal consultation and other work.
