Evaluation of Carotid Artery Elasticity in Children of Different Disease Courses with Type Ⅰ Diabetes Mellitus via RF-Data Based Quantitative Analysis on Vessel Stiffness Technique
10.3969/j.issn.1005-5185.2024.12.007
- VernacularTitle:全息血管硬度分析技术评价不同病程1型糖尿病患儿颈动脉弹性功能
- Author:
Shujiao JI
1
;
Xueyan XU
;
Haohui ZHU
;
Yulin NIU
;
Xijun ZHANG
;
Yongxing CHEN
Author Information
1. 河南省胸科医院 郑州大学附属胸科医院超声科,河南 郑州 450000
- Publication Type:Journal Article
- Keywords:
RF-data based quantitative analysis on vessel stiffness technique;
Carotid artery elasticity;
Diabetes mellitus,type 1;
Children
- From:
Chinese Journal of Medical Imaging
2024;32(12):1231-1236
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To evaluate the changes of carotid artery elasticity in children with type 1 diabetes mellitus (T1DM) via RF-data based quantitative analysis on vessel stiffness technique (R-VQS),and to detect its correlation with the duration of diabetes mellitus and blood sugar control. Materials and Methods A total of 75 children with T1DM from the Pediatrics Department of Henan Chest Hospital,the Pediatrics Department of Henan People's Hospital,and the Endocrinology,Genetics,and Metabolism Department of Henan Children's Hospital were prospectively collected from September 2019 to November 2021. According to the T1DM duration,all patients were divided into long course group (duration ≥5 years,n=30 cases) and short course group (duration<5 years,n=45 cases). And 30 age and sex matched controls were also collected. The systolic diameter (Diam),vascular displacement (Dist),pulse wave velocity (PWV),stiffness coefficient (HC) and intima-media thickness (IMT) of common carotid artery were measured by R-VQS. Fasting blood glucose (FBG),glycosylated hemoglobin (HbA1c),triglyceride (TG),serum total cholesterol (TC),high-density lipoprotein (HDL),low-density lipoprotein cholesterol (LDL) were collected to compared the differences of parameters among the three groups. Results The FBG,HbA1c and IMT of the long and short course groups were all significantly higher than those of control group (all P<0.05). There were statistically significant differences in PWV and HC among the three groups (F=22.854,P<0.001;F=16.811,P<0.001;H=33.214,P<0.001). The course of disease was moderately correlated with PWV and HC (r=0.621,0.517,respectively,P<0.001). HbA1c was moderately correlated with PWV (r=0.562,P<0.001). Conclusion Early onset of T1DM in children may lead to decreased carotid artery elasticity,and prolonged hyperglycemia can aggravate the degree of arterial elasticity damage. R-VQS is a simple,effective,and non-invasive method for assessing arterial elasticity,providing a basis for clinical diagnosis and treatment.
