Incidence of Major Pneumothorax and its Related Factors in Patients Undergoing CT-Guided Percutaneous Lung Biopsy
10.3969/j.issn.1005-5185.2024.12.017
- VernacularTitle:CT引导肺穿刺活检术后大量气胸的发生风险及相关因素分析
- Author:
Zhixin BIE
1
;
Bin LI
1
;
Yuanming LI
1
Author Information
1. 北京医院肿瘤微创治疗中心 国家医学中心 中国医学科学院医学研究院,北京 100730
- Publication Type:Journal Article
- Keywords:
Biopsy,needle;
Tomography,X-ray computed;
Pneumothorax;
Lung diseases;
Risk factors
- From:
Chinese Journal of Medical Imaging
2024;32(12):1282-1288
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To observe the risk of large pneumothorax after CT-guided percutaneous lung biopsy and analyze its associated factors. Materials and Methods This study was a prospective cohort design,enrolling 1732 patients who underwent CT-guided percutaneous lung biopsy in Beijing Hospital from January 2017 to December 2023. Patients were divided into three groups based on the occurrence and severity of pneumothorax:non-pneumothorax group (1361 cases),minor pneumothorax group (277 cases) and large pneumothorax group (94 cases). Baseline clinical data,puncture-related parameters and lesion characteristics were collected,and risk factors for major pneumothorax were analyzed. Results There were significant differences in terms of age,heart failure,lesion size,distance from the chest wall and presence of pulmonary bullae/emphysema among the three groups (F/x2=12.878,15.115,14.208,6.293,19.492,all P<0.05). Multivariate Logistic regression analysis identified the following as significant independent factors for large pneumothorax,including age≥65 years (OR=1.204,P=0.007),heart failure (OR=1.449,P=0.016),lesion size≤2 cm (OR=1.378,P=0.003),distance from chest wall≥2 cm (OR=1.311,P=0.012),presence of pulmonary bullae/emphysema (OR=2.079,P<0.001) and puncture depth≥5 cm (OR=1.405,P=0.003). Conclusion The occurrence of large pneumothorax following CT-guided percutaneous lung biopsy is closely associated with factors such as age,heart failure,lesion size,distance from the chest wall and the presence of pulmonary bullae/emphysema.
