Rare extrahepatic diseases and pathogenic mechanisms of hepatitis E virus
10.3969/j.issn.1002-2694.2024.00.179
- VernacularTitle:戊型肝炎病毒致少见肝外疾病及其致病机制
- Author:
Hao-jin ZHANG
1
;
Su-wen JIANG
;
Ai-rong HU
;
Ken LIN
;
Ying FAN
;
Jia-lan WANG
;
Meng-han JIN
;
Shi-yang FAN
;
Shi-qi YANG
Author Information
1. 绍兴文理学院医学院,绍兴 312000
- Publication Type:Journal Article
- Keywords:
hepatitis E virus;
extrahepatic diseases;
rare diseases;
pathogenic mechanism
- From:
Chinese Journal of Zoonoses
2024;40(12):1174-1181,1187
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis E virus(HEV)infection is an infectious disease that can lead to acute or chronic hepatitis E and poten-tially liver failure.HEV can invade multiple organ systems outside the liver,thus leading to pathological damage and diverse clinical manifestations.Neurological disorders are the most common extrahepatic diseases associated with HEV infection.The rare associated extrahepatic diseases include renal disorders,hematological disorders,acute pancreatitis,endocrine system dis-eases,and male infertility.Hence,HEV infection should be considered as a systemic disease rather than solely a liver disease.Many reports have described nervous system diseases caused by HEV infection.This article reviews the rare extrahepatic disea-ses and pathogenic mechanisms of hepatitis E,to enhance comprehensive,in-depth understanding of HEV infection,and to provide a reference for early identification and intervention.
