Mechanism and progress for progestin-primed ovarian stimulation protocol in the patients with polycystic ovary syndrome
10.3760/cma.j.cn101441-20231024-00174
- VernacularTitle:高孕激素状态下促排卵在多囊卵巢综合征中应用的机制及研究进展
- Author:
Yanjing BAO
1
;
Haiyan LI
;
Minyin LIU
;
Zhenbo OUYANG
;
Shiyuan WEI
;
Tianyang GAO
Author Information
1. 广东省第二人民医院生殖医学中心，广州 510317
- Publication Type:Journal Article
- Keywords:
Ovarian stimulation;
Luteal-phase stimulation;
Progestin-primed ovarian stimulation;
Fertilization in vitro;
Embryo transfer;
Polycystic ovary syndro
- From:
Chinese Journal of Reproduction and Contraception
2024;44(9):963-967
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome (PCOS) is one of the most common gynaecological endocrine diseases in women and the main cause of anovulatory infertility. Compared with women with normal ovulation, PCOS patients are more likely to face ovarian hyperstimulation syndrome, poor-quality of oocyte and fertilization failure in assisted reproduction treatment, so ovulation induction in PCOS patients has attracted much attention in the reproductive field. Progestin-primed ovarian stimulation (PPOS) protocol uses exogenous progesterone effectively to block luteinizing hormone surge to achieve ideal number of retrieved oocytes, embryo quality and pregnancy outcomes. This article reviews the mechanism, clinical application and development of PPOS protocol in PCOS patients.
