Development and challenges of reproductive pharmacology
10.3760/cma.j.cn101441-20240105-00006
- VernacularTitle:生殖药理学学科发展与挑战
- Author:
Yan ZHU
1
;
Xin ZHANG
1
;
Daxu FU
1
Author Information
1. 上海市生物医药技术研究院 国家卫健委生育调节药械重点实验室暨上海市生殖健康工程技术中心，上海 200032
- Publication Type:Journal Article
- Keywords:
Reproductive pharmacology;
Fertility protection;
Contraceptives;
Health of offspring;
Discipline progress
- From:
Chinese Journal of Reproduction and Contraception
2024;44(6):557-561
- CountryChina
- Language:Chinese
-
Abstract:
Currently, the major task of reproductive pharmacology is fertility preservation. Aside from studying the efficacy of contraceptives, the research area of reproductive pharmacology has been expanded to probe into the pharmacodynamics and the mechanism of action of medications for treatment of reproductive system disease and assisted fertility as well. The development of analysis techniques, including genomics, transcriptomics, metabolomics, proteomics, organoid culture, stem cell technology and single cell sequencing, provide multiple ways to explore therapeutic targets and new mechanisms of the treatment approaches. With the changes of age structure diagram in China population accompanied with coexisting lower fertility, higher abortion rate and increased number of seniors, more attention in the area of reproductive pharmacology should be paid on the research and development of contraceptives suitable for the young and the unmarried girls to avoid unnecessary abortion and preserve their fertility and provide more opportunities for those who willing to have children, extending their the reproductive span. Furthermore, pharmacological effects, especially the impact and outcomes of assisted reproductive technology and pertaining products on the health of the offspring should be paid more investigation and concerned, which belong to a part of the basic national policy of eugenics and are crucial to enhance the population quality of all the nationalities. This is a major challenge for the reproductive pharmacology researchers faced.
