Pharmaceutical Care for Anti-infective Therapy in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
10.3870/j.issn.1004-0781.2025.09.021
- VernacularTitle:持续肾脏替代治疗重症患者抗感染治疗的药学监护
- Author:
Hua LIU
1
;
Lifen LI
;
Changjie CAI
;
Jiahui LIN
;
Jie PAN
;
Yanzhe XIA
Author Information
1. 苏州大学附属第二医院药学部,苏州 215004
- Publication Type:Journal Article
- Keywords:
Polymyxin B;
Continuous renal replacement therapy;
Lung transplantation;
Pharmaceutical care
- From:
Herald of Medicine
2025;44(9):1508-1511
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the pharmaceutical care clinical pharmacists provide for anti-infective therapy in patients undergoing continuous renal replacement therapy(CRRT)after lung transplantation.Methods The clinical pharmacist utilized a limited sampling strategy and participated in the entire anti-infective treatment process for an adult lung transplant recipient based on pharmacokinetic monitoring results.The CRRT duration was flexibly adjusted,the dosing regimen was optimized,and adverse drug reactions were monitored.Result The clinical pharmacist assisted the physician in optimizing the polymyxin B anti-infective therapy post-transplantation,leading to successful infection control and patient discharge.Conclusion Clinical pharmacists can conduct real-time drug concentration monitoring in lung transplant patients based on pharmacokinetic characteristics,develop individualized dosing regimens,and improve medication safety and efficacy during anti-infective therapy.
