Correlation of changes in inner retinal irregularity index after idiopathic macular epiretinal membrane stripping with visual function
10.13389/j.cnki.rao.2025.0122
- VernacularTitle:特发性黄斑前膜患者黄斑前膜剥除术后内层视网膜不规则指数变化与视功能的相关性
- Author:
Xiaobo ZHU
1
;
Yan SU
;
Xiaoling YAN
;
Shuo ZHAO
;
Wenbin WEI
Author Information
1. 100078 北京市,北京中医药大学东方医院眼科;458030 河南省鹤壁市,鹤壁市人民医院眼科
- Publication Type:Journal Article
- Keywords:
idiopathic;
macular epiretinal membrane peeling surgery;
visual function;
inner retinal irregularity index
- From:
Recent Advances in Ophthalmology
2025;45(9):711-714
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between changes in the inner retinal irregularity index(IRII)af-ter macular epiretinal membrane(ERM)stripping and visual function in patients with idiopathic macular epiretinal mem-brane(IMEM).Methods A retrospective analysis was conducted on the clinical data of 134 patients(162 eyes)with IMEM who visited our hospital from March 2022 to December 2024.Based on fundus color photography and OCT findings,the patients were divided into the cellophane macular reflex(CMR)group and the preretinal macular fibrosis(PMF)group.Differences in central macular thickness(CMT),best-corrected visual acuity(BCVA),inner retinal thickness(IRT),and IRII were analyzed between the two groups.The diagnostic efficacy of these indicators for IMEM at admission was analyzed using receiver operating characteristic(ROC)curves.The differences in visual function indicators and IRII before and 3 months after ERM stripping were compared in IMEM patients.The correlation between IRII levels and visual function parameters at 3 months postoperatively was analyzed using Pearson correlation analysis.Results Among the 134 patients(162 eyes)with IMEM,93 patients(103 eyes)were in the CMR group and 41 patients(59 eyes)were in the PMF group.The CMT,IRT,and IRII were significantly lower in the CMR group than in the PMF group(all P＜0.05).The areas under the curve(AUC)for CMT,IRT,and IRII were 0.616,0.609,and 0.862,respectively(all P＜0.05).Among the 134 patients(162 eyes)with IMEM,79 patients(86 eyes,53.86％)underwent surgical treatment,and 55 patients(76 eyes,46.91％)received non-surgical treatment.Three months after surgery,the CMT,IRT,and IRII in IMEM patients were sig-nificantly lower than those before surgery(all P＜0.05).At 3 months postoperatively,CMT and IRT were significantly pos-itively correlated with IRII in IMEM patients(all P＜0.05).Conclusion CMT,IRT,and IRII all have good diagnostic ef-ficacy for IMEM staging.Moreover,IRII changes in IMEM patients who underwent macular ERM stripping are positively correlated with visual function.
