A successful case of in vitro fertilization and embryo transfer pregnancy in patients with intracranial germ cell tumors after radiotherapy
10.3760/cma.j.cn101441-20240208-00060
- VernacularTitle:颅内生殖细胞肿瘤放疗后患者体外受精-胚胎移植助孕成功1例
- Author:
Ying YU
1
;
Huilin YANG
1
;
Yingzhe LI
1
;
Jiaxin ZHANG
1
;
Yuan PAN
1
Author Information
1. 吉林大学第一医院生殖中心·产前诊断中心，长春 130000
- Publication Type:Journal Article
- Keywords:
Fertilization in vitro;
Embryo transfer;
Intracranial germ cell tumours;
Radiotherapy
- From:
Chinese Journal of Reproduction and Contraception
2024;44(9):952-954
- CountryChina
- Language:Chinese
-
Abstract:
After radiotherapy of intracranial germ cell tumors (iGCTs), female patients may suffer from hypogonadotropic amenorrhea and infertility. In this case, we investigated the selection of pregnancy assistance treatment and pregnancy assistance program for patients with iGCTs radiotherapy history. This case reported a patient with a history of radiotherapy for iGCTs who underwent fresh embryo transfer and successful pregnancy after ovulation induction with injectable human menopausal gonadotropin and recombinant human luteinizing hormone. The patient underwent cesarean section at 39 +5 weeks of gestation and delivered a healthy female infant. This pregnancy assistance scheme can provide reference for the treatment of similar patients and optimize clinical decision-making.
