Risk of Progression of Ground Glass Nodule by High-Resolution CT Pulmonary Vascular Penetration Sign
10.3969/j.issn.1005-5185.2025.02.011
- VernacularTitle:高分辨CT肺血管穿行征对肺磨玻璃结节进展的风险评估
- Author:
Fang CHEN
1
;
Hong ZHAO
;
Jingjing LIANG
;
Zongshan WU
Author Information
1. 安徽医科大学第二附属医院放射科,安徽 合肥 230601;皖西卫生职业学院附属医院影像科,安徽 六安 237000
- Publication Type:Journal Article
- Keywords:
Pulmonary nodule;
Lung neoplasms;
Adenocarcinoma;
Tomography,X-ray computed;
Risk
- From:
Chinese Journal of Medical Imaging
2025;33(2):166-170
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate whether concomitant vascular penetration in ground glass nodule(GGN)is a risk factor for progression of pulmonary nodule,and to inform the follow-up strategy of pulmonary GGN.Materials and Methods A retrospective collection of 256 patients who underwent high-resolution CT of the chest and were diagnosed as containing persistent GGN(initial diameter≤10 mm)at the Affiliated Hospital of West Anhui Health Vocational College from January 2016 to November 2023 was performed.The nodules were categorized into the group with pulmonary vascular penetration(group A)and the group without pulmonary vascular penetration(group B)according to whether or not pulmonary vascular penetration was present within the GGN on chest high-resolution CT images.The progression of GGN was judged by evaluating the changes in imaging features such as size and density,and the progression-free survival of the nodules between the two groups was compared.Results Among 256 patients,155 patients(196 GGN)were divided in group A and 101 patients(106 GGN)in group B.During 14 to 80 months period,31 nodules had progressed,and the rate of GGN progression was 10.3%(31/302).Nodes in both groups had the same progression-free survival rate at 1 year of follow-up,and there was a flat decline in progression-free survival rate from 2 to 5 years of follow-up,but the differences in progression-free survival between different follow-up time nodes(36,60 and 80 months)were not statistically significant in either group(χ2=2.880,P=0.090;χ2=1.683,P=0.194;χ2=2.630,P=0.105).Conclusion The presence of pulmonary vascular penetration in pulmonary GGN is a common presentation and is not an independent risk factor for nodule progression,and cannot be used as an indicator of the risk of nodule malignancy and surgical intervention.
