Application of long-read sequencing in preimplantation genetic testing
- VernacularTitle:长读长测序技术在胚胎植入前遗传学检测中的应用
- Author:
Cheng WAN
1
;
Taoli DING
1
;
Jieliang MA
1
;
Xingxing WANG
1
;
Ji YANG
1
;
Sijia LU
1
Author Information
- Publication Type:Journal Article
- Keywords: Reproductive health; Preimplantation genetic testing; Long-read sequencing; Clinical application
- From: Chinese Journal of Reproduction and Contraception 2024;44(2):188-192
- CountryChina
- Language:Chinese
- Abstract: In recent years, the long-read sequencing technology has been developing rapidly, playing a crucial role in research fields of genomics, transcriptomics, and epigenetics, and showing broad application prospects in the field of clinical testing. This paper introduces the basic principles and performance of the main long-read sequencing platforms, reviews the research progress of this technology in preimplantation genetic testing, and discusses the major challenges currently faced and possible future directions.
