Quality control of preimplantation genetic testing
10.3760/cma.j.cn101441-20240403-00111
- VernacularTitle:胚胎植入前遗传学检测技术质量控制
- Author:
Xinrui LIU
1
;
Sexin HUANG
1
;
Ming GAO
1
;
Yang ZOU
1
;
Yuan GAO
1
Author Information
1. 山东大学妇儿与生殖健康研究院 山东大学附属生殖医院分子遗传室 山东大学生殖医学与子代健康全国重点实验室，济南 250012
- Publication Type:Journal Article
- Keywords:
Preimplantation genetic testing;
Quality control;
Standard operating procedures
- From:
Chinese Journal of Reproduction and Contraception
2024;44(7):696-699
- CountryChina
- Language:Chinese
-
Abstract:
With the increasing application scale of preimplantation genetic testing (PGT), the role of molecular genetic testing technology in the clinical diagnosis and treatment of assisted reproductive technology is also rapidly improving. The stability, reliability and validity of PGT results are important guarantees for the subsequent precise embryo screening, and laboratory quality control and management are essential for the clinical application of PGT. The content of PGT quality control can be summarized as personnel, equipment, materials, methods, environment, and pre-test, in-test and post-test, which cover all aspects of whole clinical process of PGT. In order to make clinical PGT practice more standardized, the quality management of each PGT step is analyzed and discussed in this article, so as to provide reliable laboratory diagnosis and treatment basis for high-quality clinical practice.
