Lifestyles, environmental factors, and commonly used drugs affecting sperm motility
10.3760/cma.j.cn101441-20240129-00046
- VernacularTitle:影响精子活力的生活方式、环境因素和常用药物
- Author:
Jiajia LAI
1
;
Yanran WANG
1
;
Shuwei ZHANG
1
;
Jiayi HU
1
;
Zeyu ZHU
1
;
Kun LI
1
Author Information
1. 杭州医学院药学院,杭州 310013
- Publication Type:Journal Article
- Keywords:
Sperm motility;
Age;
Obesity;
Smoking;
Diet;
Temperature;
Asthenozoospermia;
Drug
- From:
Chinese Journal of Reproduction and Contraception
2024;44(6):587-593
- CountryChina
- Language:Chinese
-
Abstract:
Sperm motility, a crucial function of sperm, refers to the ability of sperm to move progressively forward. Only sperm with adequate motility can reach the fertilization site and successfully recognize and fuse with an egg during natural reproduction. Asthenozoospermia, defined by a percentage of progressive sperm below the reference value's lower limit, is one of the most prevalent causes of male infertility. Sperm motility maintenance relies on both a normal flagellar structure and signal transduction pathways. However, extracellular environmental factors related to motility are also of significant importance. This review addresses factors influencing sperm motility, encompassing lifestyles, environmental elements, and commonly used drugs. It offers valuable insights for the prevention and diagnosis of asthenozoospermia and supports the strategies for preventing male infertility.