Multi spiral CT study on upper airway obstruction characteristics in patients with obstructive sleep apnea hypopnea syndrome
10.3969/j.issn.1002-1671.2025.09.007
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征患者上气道阻塞特征分析的多层螺旋CT研究
- Author:
Min LI
1
;
Zewei WANG
1
;
Lingbo MENG
1
;
Juling DUN
1
Author Information
1. 北京市大兴区中西医结合医院放射科,北京 100076
- Publication Type:Journal Article
- Keywords:
obstructive sleep apnea hypopnea syndrome;
upper airway anatomy;
multi spiral computed tomography;
risk factors
- From:
Journal of Practical Radiology
2025;41(9):1453-1457
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the characteristics of upper airway obstruction on multi spiral computed tomography(MSCT)in patients with obstructive sleep apnea hypopnea syndrome(OSAHS)and their correlation with the disease,as well as to identify key characteristic indicators.Methods Forty-three patients with OSAHS(OSAHS group)and 45 normal controls(control group)were selected.MSCT of the upper airway was performed to analyze the differences in various observation indicators between the two groups,including diameters at levels of upper airway obstruction,soft palate thickness,mandibular plane to hyoid distance(MP-H),oropharyngeal length,air-pharyngeal ratio,and fat infiltration in the tongue base.A multivariate logistic regression model was con-structed to identify the main risk factors,and the receiver operating characteristic(ROC)curve was used to assess the diagnostic per-formance of the model.Results The OSAHS group exhibited smaller diameters at levels of upper airway obstruction and air-pharyn-geal ratio compared to the control group[area:(0.75±0.38)cm2 vs(1.36±0.58)cm2,t=5.855,P＜0.001].Additionally,body mass index(BMI),degree of fat infiltration in the tongue base,soft palate thickness,and MP-H were significantly greater in the OSAHS group than those in the control group(soft palate thickness:t=-6.881,P＜0.001).Multivariate logistic regression analysis revealed that fat infiltration in the tongue base,soft palate thickness,MP-H,and the area of upper airway obstruction were the main risk factors for OSAHS.The area under the curve(AUC)was 0.940[95％confidence interval(CI)0.868-0.979,P＜0.001],indica-ting good diagnostic performance.Conclusion MSCT can effectively evaluate the upper airway obstruction characteristics in patients with OSAHS,with fat infiltration in the tongue base,soft palate thickness,MP-H,and the area of upper airway obstruction as the primary indicators for OSAHS,providing a reference for clinical practice.
