Research progress on the impact of scarred uterus after cesarean section on the pregnancy outcomes of assisted reproductive technology
10.3760/cma.j.cn101441-20230829-00093
- VernacularTitle:剖宫产瘢痕子宫对辅助生殖技术助孕结局影响的研究进展
- Author:
Jiayi WANG
1
;
Hui JI
1
;
Xiufeng LING
1
Author Information
1. 南京医科大学附属妇产医院（南京市妇幼保健院）生殖中心，南京 210004
- Publication Type:Journal Article
- Keywords:
Cesarean section;
Cicatrix;
Reproductive techniques, assisted;
Pregnancy outcome;
Secondary infertility
- From:
Chinese Journal of Reproduction and Contraception
2024;44(8):847-852
- CountryChina
- Language:Chinese
-
Abstract:
Due to the formation of scars in the local uterus during cesarean section, the subsequent natural pregnancy of these patients is affected and they receive assisted reproductive technology (ART) for pregnancy treatment. However, the impact of cesarean section on the pregnancy outcomes of ART is still controversial. Studies have shown that poor scar healing after cesarean section is related to changes in uterine anatomy, weakened endometrial receptivity, and imbalance in uterine microenvironment, which is not conducive to embryo implantation and increases the risk of recurrent implantation failure and recurrent miscarriage. Scar diverticulum repair is an effective method to improve the pregnancy outcomes of patients with scarred uterus. In recent years, uterine perfusion, inhibition of uterine contractions, and the application of antibiotics have also become new ideas to improve the uterine environment. Based on the relationship between cesarean section scarred uterus and subsequent fertility, this article reviews the possible mechanisms and treatment options that affect the pregnancy outcomes of ART, providing clinical evidence for daily practice.
