Research progress of vitamin D receptor in endometriosis
10.3760/cma.j.cn101441-20240302-00079
- VernacularTitle:维生素D受体在子宫内膜异位症中的研究进展
- Author:
Xiaohan TANG
1
;
Meisong LU
1
Author Information
1. 哈尔滨医科大学附属第一医院妇产科，哈尔滨 150001
- Publication Type:Journal Article
- Keywords:
Endometriosis;
Vitamin D receptor;
Vitamin D
- From:
Chinese Journal of Reproduction and Contraception
2024;44(10):997-1001
- CountryChina
- Language:Chinese
-
Abstract:
Endometriosis is a common chronic gynecological disease and leads to continuous aggravation of pelvic adhesion, pain and infertility, which seriously affects women's fertility and quality of life. Studies related to vitamin D and endometriosis have received increasing attention, the response of vitamin D in target organs depends on the expression level and biological function of vitamin D receptor (VDR). Thus, the function and characteristics of VDR were summarized in this study, and the expression level, gene polymorphism, mechanism of VDR in endometriosis and the research progress of VDR agonists in the treatment of endometriosis were reviewed, providing new ideas for basic and clinical research on diagnosis and treatment of endometriosis.
