Research progress of transcriptomic study in adenomyosis
10.3760/cma.j.cn101441-20230904-00104
- VernacularTitle:子宫腺肌病转录组学研究进展
- Author:
Zhuoying TANG
1
;
Feiyang DIAO
1
Author Information
1. 南京医科大学第一附属医院生殖医学中心，南京 210029
- Publication Type:Journal Article
- Keywords:
Adenomyosis;
Transcriptome analysis;
Microarray;
RNA sequencing;
Single-cell RNA sequencing;
Endometrial receptivity array
- From:
Chinese Journal of Reproduction and Contraception
2024;44(5):531-536
- CountryChina
- Language:Chinese
-
Abstract:
Adenomyosis is a common gynecological disease with the main clinical manifestations of pelvic pain, abnormal uterine bleeding and reproductive disorders. At present, there is no unified evaluation criteria and treatment plan for adenomyosis, so it is important to understand the molecular mechanism of adenomyosis. Transcriptomics explains the functional elements of the genome at a global level and reveals the molecular mechanisms in specific biological processes. In recent years, with the rapid development of transcriptomics analysis technology, a number of studies have explored the molecular mechanism of adenomyosis based on transcriptomics, identified biomarkers and potential therapeutic targets of adenomyosis, and provided a new perspective for the diagnosis and treatment of adenomyosis. This review focuses on the latest research advances in transcriptome analysis in adenomyosis.
