Effectiveness of Transcatheter Closure Treatment of Ventricular Septal Defect Without Distance From the Aortic Valve With Eccentric Occluder
10.3969/j.issn.1000-3614.2025.08.010
- VernacularTitle:偏心封堵器介入治疗距主动脉瓣零距离室间隔缺损的疗效观察
- Author:
Zirui SUN
1
;
Yu HAN
;
Shubo SONG
;
Yan HAN
;
Lele BEN
;
Taibing FAN
;
Gejun ZHANG
Author Information
1. 阜外华中心血管病医院(郑州大学附属华中阜外医院)河南省人民医院心脏中心 结构性心脏病病区,郑州 450000
- Publication Type:Journal Article
- Keywords:
aortic valve without distance;
ventricular septal defect;
transcatheter occlusion;
eccentric occluder
- From:
Chinese Circulation Journal
2025;40(8):795-798
- CountryChina
- Language:Chinese
-
Abstract:
Objectives:To evaluate the feasibility and clinical efficacy of eccentric occluder for the treatment of ventricular septal defect(VSD)without distance from the aortic valve.Methods:This analysis included 16 patients(9 males and 7 females)with VSD without distance from the aortic valve,who were treated at Fuwai Central China Cardiovascular Hospital from February 2022 to June 2024.Ten cases had mild right coronary sinus prolapse,and 2 had mild aortic valve regurgitation.All patients were diagnosed with VSD located zero-distance from aortic valve through transthoracic echocardiography(TTE)and left ventricular angiography.Eccentric occluder was used for interventional closure.TTE and 12-lead electrocardiography(ECG)were performed at 1 month,3 months,and 6 months after surgery to observe the presence of residual shunt,aortic valve regurgitation,and cardiac electrical conduction abnormalities.Results:Transcatheter closure was successful in 15 patients,procedure failed in one patient due to the unstable fixation of the occluder.Average diameter of the defect is(4.37±1.53)mm,and the diameter of the occluder is 6.5(6.0,8.0)mm.Postoperative left ventricular angiography showed minimal residual shunt in 3 cases,and no complications such as pericardial tamponade,hemolysis,thromboembolism,or infection,were observed.At one month after occlusion,TTE results showed that residual shunt disappeared in 3 patients with residual shunt.During 3-month and 6-month follow-up,all the occluders were well-positioned with no new aortic valve regurgitation or worsening of the original regurgitation,and no atrioventricular block or bundle branch block and other electrocardiographic conduction abnormalities.Conclusions:The use of eccentric occluder for intervention of ventricular septal defect patients without distance from the aortic valve is safe and effective.
