Excessive prenatal testosterone of patients with polycystic ovarian syndrome affects the reproductive system of male offspring: a review
10.3760/cma.j.cn101441-20230614-00238
- VernacularTitle:PCOS患者妊娠期过量睾酮影响男性子代生殖发育的机制研究进展
- Author:
Chao LIAN
1
;
Yu ZHOU
;
Rong JU
;
Jianquan CHEN
Author Information
1. 南京医科大学附属江宁医院中心实验室，南京 210000
- Publication Type:Journal Article
- Keywords:
Testosterone;
Spermatogenesis;
Polycystic ovarian syndrome;
cAMP response element binding protein
- From:
Chinese Journal of Reproduction and Contraception
2024;44(5):541-547
- CountryChina
- Language:Chinese
-
Abstract:
High androgen levels are one of the typical features of patients with polycystic ovarian syndrome. Excessive prenatal testosterone not only affects the reproductive health of female offspring, but also affects male reproductive health. This article reviews the mechanisms of excessive prenatal testosterone affecting reproductive development and spermatogenesis on male offspring. This article aims to provide reference for the mechanism research and clinical intervention of excessive prenatal testosterone affecting reproductive health of male offspring.
