Exploring the Pathogenesis and Syndrome Treatment of Radiation-Induced Skin Injury Based on the"Fire-Toxin Pathogenesis"Theory
10.14148/j.issn.1672-0482.2025.1641
- VernacularTitle:从"火毒致病"探讨放射性皮肤损伤的病因病机及证治思路
- Author:
Yan WU
1
;
Yi JI
;
Jinbiao ZHU
;
Mianhua WU
Author Information
1. 南京中医药大学附属医院,江苏 南京 210029
- Publication Type:Journal Article
- Keywords:
radiation-induced skin injury;
fire-toxin pathogenesis;
stagnant heat;
syndrome differentiation and treatment;
experi-ence of renowned doctors
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(12):1641-1646
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced skin injury is a common complication in tumor radiotherapy,which seriously affects patients'quality of life and treatment continuity.Based on the theory of"fire-toxin pathogenesis",Professor Wu Mianhua,a renowned national tradi-tional Chinese medicine(TCM)practitioner,holds that its core pathogenesis is"external attack by fire-toxin,damage to yin and con-sumption qi,and blood stasis obstructing the skin and muscles".The course of the disease presents a dynamic evolution of acute stage(blazing heat-toxin),subacute stage(yin deficiency and blood stasis),and chronic stage(deficiency of both qi and yin).In terms of treat-ment,the principles of"syndrome differentiation by stages and simultaneous treatment of root cause and symptoms"are adopted:clear-ing heat and resolving toxin,cooling blood and reducing swelling in the acute stage;nourishing yin and moistening dryness,clearing heat and dissolving stasis in the subacute stage;and benefiting qi and nourishing yin,dissipating stasis and unblocking collaterals in the chronic stage.Emphasis is laid on the combination of internal and external treatment as well as the integration of prevention and treatment.This paper systematically sorts out Professor Wu Mianhua's academic thoughts on exploring the pathogenesis and syndrome treatment of radiation-induced skin injury using the"fire-toxin pathogenesis"theory,and attaches analysis of proven cases,so as to provide theoretical and practical references for clinical practice.
