Interpretation of the Cancer Toxin Pathogenesis Theory in Esophageal Cancer from the Perspective of Knowledge History
10.14148/j.issn.1672-0482.2025.1633
- VernacularTitle:知识史视域下食管癌癌毒病机理论诠释
- Author:
Yihang LOU
1
;
Jiahao WANG
;
Haibo CHENG
;
Renshou CHEN
Author Information
1. 南京中医药大学中医药文献研究院,江苏 南京 210023
- Publication Type:Journal Article
- Keywords:
pathogenesis theory of cancer toxin;
knowledge history;
esophageal cancer
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(12):1633-1640
- CountryChina
- Language:Chinese
-
Abstract:
From the perspective of the knowledge history,the development of traditional Chinese medicine(TCM)knowledge re-lated to esophageal cancer began with early records of"difficulty in swallowing"during the Qin and Han dynasties.Through the accu-mulation of symptom-treatment experience during the Wei and Jin dynasties,it shifted towards theoretical exploration during the Song and Yuan dynasties,clarifying the pathogenesis of stomach cold,phlegm qi,and blood stasis,and so on.By the Ming and Qing dynas-ties,a rudimentary system for the syndrome differentiation of esophageal cancer was gradually formed,and the characteristic of"esopha-geal stricture"in this disease was identified.Finally,in the late Qing dynasty,Western medicine introduced the concept of"cancerous swelling".The current theory of cancer toxin pathogenesis,with cancer toxin pathogenesis at its core,innovatively integrates related knowledge,representing a reconstruction and transformation of traditional knowledge in the context of the new era.The relevant knowl-edge from past dynasties serves as both the premise and foundation for the innovation of the cancer toxin pathogenesis theory,and it also inspires new vitality in clinical practice through this theory,providing insights and methodologies for the innovation of modern TCM theory.
