Research progress of oral hairy leukoplakia
10.13591/j.cnki.kqyx.2025.08.011
- VernacularTitle:口腔毛状白斑的研究进展
- Author:
Longhui MO
1
;
Jing LIANG
;
Jiongke WANG
;
Tiannan LIU
;
Xin ZENG
Author Information
1. 四川大学华西口腔医院口腔黏膜病科,口腔疾病防治全国重点实验室,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔黏膜病国家临床重点专科,中国医学科学院口腔黏膜癌变与防治创新单元,四川成都(610041)
- Publication Type:Journal Article
- Keywords:
oral hairy leukoplakia;
EBV(Epstein-Barr virus);
pathogenesis;
diagnosis;
antiviral therapy
- From:
STOMATOLOGY
2025;45(8):624-630
- CountryChina
- Language:Chinese
-
Abstract:
Oral hairy leukoplakia is an oral mucosal disease caused by Epstein-Barr virusinfection of oral squamous epithelial cells.Oral hairy leukoplakia presents as a non-removable,corrugated and wrinkled white plaque sometimes with hair-like projections,typical-ly occurring on the border of the tongue.It is commonly found in patients infected by human immunodeficiency virus,and it can also be seen in immunocompetent and immunocompromised patients who are not infected by human immunodeficiency virus.The pathogenesis of oral hairy leukoplakia is still unclear,and anti-EBV therapy is the main treatment for oral hairy leukoplakia at present.This paper will review the etiology,pathogenesis,risk factors,epidemiology,clinical manifestations,diagnosis and treatment of oral hairy leuko-plakia.