Research progress on the effects of chromatin remodeling factors on mammalian gametogenesis and early embryonic development

VernacularTitle:染色质重塑因子对哺乳动物配子发生及早期胚胎发育进程影响的研究进展
Author: Renyun HONG ¹ ; Yuanjiao LIANG ¹
Author Information

1. 东南大学附属中大医院生殖医学科，南京　210009
Publication Type:Journal Article
Keywords: Chromatin remodeling factors; Gametogenesis; Early embryonic development; Mammal
From: Chinese Journal of Reproduction and Contraception 2024;44(2):201-204
CountryChina
Language:Chinese
Abstract: There are various types of chromatin remodeling factors in eukaryotes, which can be divided into four categories: SWI/SNF, ISWI, CHD and INO80, according to the differences of ATPase and other constituent protein subunits. These remodeling factors affect gene transcription regulation through changes in chromatin structure to ensure the accurate operation of various biological processes in cells. At present, the role of chromatin remodeling factors in mammalian gametogenesis and early embryonic development is not widely studied. In this paper, we will make a brief review to provide theoretical basis for further understanding of the functions about the chromatin remodeling factors in reproductive development.