Current status and research progress in the development of cryopreservation of human germ cells
10.3760/cma.j.cn101441-20221229-00593
- VernacularTitle:人类生殖细胞低温冷冻保存现状与研究进展
- Author:
Ran JIANG
1
;
Jingyi HU
1
;
Guidong YAO
1
Author Information
1. 郑州大学第一附属医院生殖医学中心，郑州 450052
- Publication Type:Journal Article
- Keywords:
Oocytes;
Sperm;
Testicular tissue;
Embryos;
Ovarian tissue;
Cryopreservation
- From:
Chinese Journal of Reproduction and Contraception
2024;44(1):103-108
- CountryChina
- Language:Chinese
-
Abstract:
Cryopreservation of human germ cells as a form of fertility preservation plays an important role in the development of assisted reproductive technology (ART), which has become one of the research hotspots in the field of reproductive medicine and is increasingly used in assisted reproductive practice. To improve the success rate of ART, cryopreservation techniques are constantly being improved in development, especially the selection of freezing strategies and the improvement and optimization of cryoprotectants. Cryopreservation is indicated for groups undergoing ART or for the freezing and preservation of oocytes, sperm and embryos due to reduced fertility caused by disease. It is also indicated for the cryopreservation of ovarian and testicular tissue for fertility preservation in cancer patients. However, the freezing effect of different freezing methods is not consistent for different germ cell types, and there is a lack of reasonable and valid criteria for evaluating the freezing effect of different germ cells. This paper reviews the current development and application of cryopreservation technology for human germ cells and discusses the future development of cryopreservation.
