Research progress of DNA methylation in embryo and fetal development of assisted reproductive technology
10.3760/cma.j.cn101441-20230315-00102
- VernacularTitle:DNA甲基化在辅助生殖技术胚胎及胎儿发育中的研究进展
- Author:
Ajiao SUN
1
;
Zhengfang XIONG
Author Information
1. 青海大学研究生院，西宁 810016
- Publication Type:Journal Article
- Keywords:
DNA methylation;
Embryonic development;
Reproductive technology,assisted;
Controlled ovarian stimulation
- From:
Chinese Journal of Reproduction and Contraception
2024;44(4):419-423
- CountryChina
- Language:Chinese
-
Abstract:
Assisted reproductive technology (ART) is considered to be an important means to help infertile women get pregnant. With the development of technology, the safety of ART has been paid more and more attention. However, the neonatal pregnancy outcome of ART is worse than that of natural conception. The operation of ART may affect the development and health of offspring through epigenetic mechanisms. DNA methylation is the most studied epigenetic regulatory mechanism. This article briefly reviewed the research progress of DNA methylation in ART embryo and fetal development, aiming to provide a new idea for clinical treatment.
