Biological function of L-carnitine in oocyte maturation and early embryo development
10.3760/cma.j.cn101441-20230410-00148
- VernacularTitle:左旋肉碱在卵母细胞成熟和早期胚胎发育中的生物学作用
- Author:
Lilan SUN
1
;
Pingping SUN
1
;
Wenjie ZHAO
1
;
Huagang MA
1
Author Information
1. 潍坊市人民医院生殖医学中心，潍坊 261000
- Publication Type:Journal Article
- Keywords:
L-carnitine;
Oocyte;
Lipid metabolism;
Antioxidants;
Apoptosis;
Embryo
- From:
Chinese Journal of Reproduction and Contraception
2024;44(6):661-665
- CountryChina
- Language:Chinese
-
Abstract:
Poor oocyte quality is responsible for female infertility. The search for supplements to improve oocyte quality is receiving increasing attention. Many studies have shown that L-carnitine plays a variety of roles in regulating female fertility. This article reviews the key roles and regulatory mechanisms of L-carnitine in oocyte maturation and early embryonic development, including activating fatty acids for β-oxidation to regulate energy metabolism, antioxidation to prevent oxidative damage, and inhibition of cell apoptosis, and the research progress of LC in improving oocyte quality and early embryo development.
