Comparison of perioperative indicators and 1-year follow-up outcomes between radical prostatectomy conducted within 2 weeks versus no earlier than 4 weeks after prostate biopsy
10.3969/j.issn.1009-8291.2025.08.003
- VernacularTitle:前列腺穿刺活检术后2周内与不少于4周后行前列腺癌根治术的围手术期指标及1年随访对比
- Author:
Kulaixi AINIWAER
1
;
Qianyue LI
;
Wenbo LU
;
Kadier WUPUER
;
Ailiyaer AIKESHANJIANG
;
Guofan DONG
;
Feng HAN
;
Yunze WANG
;
Jianwei SUN
;
Wenguang WANG
Author Information
1. 新疆医科大学第一附属医院泌尿中心,新疆乌鲁木齐 830054
- Publication Type:Journal Article
- Keywords:
prostate biopsy;
laparoscopic radical prostatectomy;
prostate cancer;
operation timing
- From:
Journal of Modern Urology
2025;30(8):648-652,661
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the impact of the interval time(IT)between prostate biopsy(PB)and radical prostatectomy(RP)on the perioperative safety and prognostic efficacy of prostate cancer patients.Methods A retrospective analysis was performed on 87 patients who underwent extraperitoneal laparoscopic RP at our hospitals during Jun.2022 to Nov.2024.The patients were divided into the IT ≤2 weeks group(n=42)and the IT ≥4 weeks group(n=45)according to the interval between PB and RP.Baseline data,perioperative indicators,postoperative inflammatory factors,postoperative pathological results,urinary continence,and complication rates were compared between the two groups.Results No statistically significant differences were observed between the two groups in baseline information,operation time,intraoperative blood loss,intraoperative transfusion rate,postoperative hospital stay,catheter removal time,inflammatory factors and complications(P＞0.05).Pathological results showed no significant differences in cancer tissue proportion,positive rate of lymph node,positive rate of surgical margins,and postoperative Gleason scores(P＞0.05).However,the IT ≤2 weeks group exhibited significantly fewer cases of perineural invasion(25 vs.36,59.52％vs.80.00％)and vascular invasion(5 vs.12,11.90％vs.26.67％)compared to the IT≥4 weeks group(P＜0.05).There were no significant differences in postoperative urinary control rate and prostate-specific antigen(PSA)level between the two groups(P＞0.05).Conclusion Radical prostatectomy performed ≤2 weeks after prostate biopsy demonstrates better safety and prognosis.
